Does CBD lotion numb pain?

CBD can provide temporary relief from discomfort, but not directly. CBD interacts with receptors throughout your body's endocannabinoid system, which plays a critical role in regulating pain and inflammation. When applied topically, CBD interacts with receptors just below the surface of the skin. This interaction sends signals that trigger the natural modulation of pain signals, which you experience as relief. So, while the potency and other ingredients in a lotion play a role in how effective it will be, you can typically count on a CBD lotion to provide short-term relief.